Staphylococcal scalded skin syndrome
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Кӯдаки бо Staphylococcal scalded skin syndrome
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ReferencesStaphylococcal Scalded Skin Syndrome ҳолате мебошад, ки дар он пӯст аз сабаби токсинҳои истеҳсолшуда аз ҷониби намудҳои муайяни бактерияҳои Staphylococcus рафъ мешавад. Ин ҳолат одатан дар кӯдакони аз шаш моҳ ба боло ба вуҷуд меояд. Он инчунин метавонад дар калонсолоне, ки системаи иммунии заиф ё мушкилоти ҷиддии гурда доранд, рӯй диҳад. Хусусияти асосии ин беморӣ пӯсти васеъшаванда пас аз илтиҳоб мебошад. Шиддат аз чанд блистер то талафоти густурдаи пӯст, ки метавонад боиси пастшавии ҳарорати бадан ва ноустувории фишори хун гардад, фаро мегирад.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
Кӯдаки 10-моҳа бо оби бинӣ омад ва ғизои хуб нахӯрд. Табибон гуфтанд, ки ин сирояти роҳҳои болоии нафас аст. Пас аз ду рӯз, ӯ баргашт, зеро беҳтар нашуд ва мушкилоти нав дошт, ба монанди варами рӯй ва пӯсти хашмгин дар атрофи даҳон. Дар давоми ду рӯзи дигар кӯдак бадтар шуд. Дасту пояш варам карда, пусташ канда шуд. Бозгашт ба беморхона, табибон доғи сурхро дар рӯи ӯ ва дар қабатҳои пӯсташ мушоҳида карданд, ки ҳангоми ламс сафед мешуд. Онҳо ба ӯ staphylococcal scalded skin syndrome (SSSS) ташхис карданд ва ба антибиотикҳо тавассути раг оғоз карданд.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
Духтарчаи 2-сола дар тамоми баданаш доғе пайдо кард, ки дар тӯли 48 соат пас аз газидани ҳашарот дар рӯяш як рӯз пеш пайдо шуд. Ҳангоми муоина дар вай доғҳои паҳншудае пайдо шуд, ки аз гулӯлаҳои хурде, ки ба ҳам мепайванданд, иборат буда, ҳангоми сабук молидани пӯсташ аломатҳои Никольскийро нишон доданд. Дар луобпардаи вай ягон аломати доғҳо дида намешуд. Санҷишҳо дар хуни ӯ ягон аломати сироятро нишон надоданд.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
Синдром аз ҷониби экзотоксинҳои эпидермолитикӣ (эксфолиатин) А ва В, ки аз S. aureus бароварда мешаванд, ба вуҷуд меояд. Пешгӯии Staphylococcal scalded skin syndrome дар кӯдакон аъло аст; бемор одатан дар давоми 10 рӯз бо табобати пурра беҳтар мешавад ва бе ҷароҳати назаррас. Бо вуҷуди ин, Staphylococcal scalded skin syndrome бояд бо некролизи заҳрноки эпидермалӣ, ки пешгӯии бад дорад, бодиққат фарқ карда шавад.
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Ташхиси нодуруст, масалан ҳамчун захмҳои экзема, дерматити атопикӣ ё истифодаи креми стероидӣ, метавонад ҷароҳатҳоро шадидтар кунад. Лутфан, агар равғани антибиотик истифода баред, ҳарчи зудтар ба духтур муроҷиат кунед.
#Bacitracin
#First-generation cephalosporins (e.g. Cefradine)
#Bacterial culture
#Third-generation cephalosporins (e.g. Cefditoren Pivoxil)